Where do most pancreatic tumors typically occur?

Most pancreatic tumors typically occur in the head of the pancreas. This is significant because the head of the pancreas is where the bile duct enters the pancreatic duct, making it a common site for tumor formation. Tumors in this area are often associated with obstructive jaundice due to their proximity to the bile duct.

Pancreatic adenocarcinomas, which are the most common type of pancreatic cancer, are particularly prevalent in the head, accounting for the majority of cases. This anatomical feature contributes to the clinical presentation and can impact treatment decisions, as tumors in the head may be more identifiable and accessible for surgical resection than those in the tail or body of the pancreas. Furthermore, the head's location often results in earlier detection due to the associated symptoms and complications, such as weight loss and jaundice, prompting patients to seek medical attention sooner.